Antibacterial Cavity Cleansing Effect from MDPB
Studies show that the risk of bacteria remaining in a cavity tends to increase with the smaller, “minimal intervention” cavities. Many doctors are using cavity cleansers, such as Consepsis (Ultradent) (LINK) to address this tendency. Clearfil SE Protect contains a new functional monomer MDPB, which exhibits an “Antibacterial Cavity Cleansing Effect.” The antimicrobial effect with Clearfil SE Protect is greater than with current cavity cleansers, and is biologically safe because MDPB is fixed and will not leak after curing. The bactericidal mechanism of MDPB is presumed to be similar to the well-known antibacterial agent CPC (Cetyl pyridinium chloride), which is in many toothpastes and mouth rinses.
Clearfil SE Protect contains a patented, specially-treated sodium fluoride (NaF); the NaF in Cleafil SE Protect is coated with a unique polymer capsule that allows release of NaF while the bonding layer physical properties, including strength, are maintained. Clearfil SE Protect makes an “acid-base resistant zone” (called Super Dentin) interface between the bond and dentin behind the hybrid layer as a result of the fluoride release. This zone is 1.2 μm, which is thicker than the hybrid layer and very important for resisting the acid generated by bacteria if microleakage does occur.